Lets start with the sandy beaches, warm water, and fantastic weather. Signs announcing the use of animals in a clinical area must be posted for 14 days prior to use at high traffic areas throughout the hospital. C. Gas anesthesia (using a vaporizer) is generally optimal for providing extended anesthesia. To conduct voluntary evaluations of institutional animal care and use programs. C. Survival AAALAC International is a private, nonprofit organization that promotes humane treatment of animals in science through a voluntary international accreditation program. A. To identify alternate approaches to a scientific problem so that research roadblocks can be avoided. Members of the Council are chosen to serve based on their extensive experience in the fields of veterinary medicine, laboratory animal science or animal research, and their commitment to humane animal care and use. A. Nonaseptic surgical practices are acceptable when it can be shown that mice do not develop postsurgical infections. Accreditation by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International has long been trumpeted as being the "gold standard" It reflects the many linkages that tie channel members and other agencies together in the DOWNLOADS Since August 23, 2010 COinS Page 2 PDF Editorial Volume 4, Issue 3Ciorstan J. Smark PDF Book Review : Social and Environmental AccountingLee C. Moerman Page 3 PDF Editorial Volume What is the maximum number of emission lines when the excited electron of a H atom in n = 6 drops to the ground state? These consultants assist the Council members with their evaluations and provide expertise in specific areas, such as management, international regulations, or certain scientific specialties. B. The needle tip should be inserted behind the incisors. If the IACUC determines that an activity must be halted, and if the organization accepts PHS funds or is registered with USDA as a research organization, any protocol suspension must be reported by the Institutional Official to, respectively OLAW and USDA. Biosafety in Microbiological and Biomedical Laboratories, Recombinant DNA inserted into the genome of transgenic mice may NOT be covered by the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules. The three Rs of Russell and Burch stand for what? These institutions volunteer to participate in AAALAC's program, in addition to complying with the local, state and federal laws that regulate animal research. When assessing a client with partial-thickness burns over 60% of the body, which finding should the nurse report immediately? The investigator To track for the presence of pain or distress in mice over time, the baseline should be based on: The signs observed on normal, untreated animals. A. These Consultants/Specialists assist the Council members with their evaluations and provide expertise in specific areas, such as management, international regulations, or certain scientific specialties. When animals are used, AAALAC works with institutions and researchers to serve as a bridge between progress and animal well-being. B. A practicing scientist with experience in animal research, person who is not a scientist, person who is not affiliated with the organization, and public relations specialist. $$ Blood collection from a superficial vessel of a dog. B. Major survival surgery on rodents The program must include time spent outside. Assist with writing the basic science portions of a grant application The USDA requires documentation of all postoperative care and retention of records for one year after the death of the animal. Which of the following statements is TRUE about pain in rodents? Which activity would place a study in pain category B? Conduct reviews of the animal care and use program on a semiannual basis, Institutional Animal Care and Use Committee. B. Which of the following is an example of refinement? Ear punching and notching is the most permanent way to identify rodents. Which types of animals must have access to environmental enrichment, as mandated by the Animal Welfare Regulations? Compliance with environmental standards in facilities housing mice is generally the responsibility of: Which of the following statements about lymphocytic choriomeningitis (LCM) is False? A. Behavioral reasons (such as aggression by C57BL/6 male mice) If the incision site on the skin is disinfected with iodine or chlorhexidine compounds, hair clipping is not necessary. Institutional Animal Control and Use Committee Long-term anesthesia is best achieved by repeat dosages of a short-acting injectable anesthetic cocktail. Creates additional regulations and guidelines that govern animal use. C. Dry ice is an acceptable source of CO2 for euthanasia. I went through the test 5 times and encountered these 63 questions on November 29th, 2018. Which of the following is TRUE regarding the Animal Welfare Regulations and duplication of experiments? Who is responsible for the humane treatment of experimental animals? Is that even a thing? ${ }_{36}^{87} \mathrm{Kr} \longrightarrow-0 \beta+$. To conduct voluntary evaluations of institutional animal care and use programs. Enrollment in the institutional Occupational Health and Safety program is mandatory before working with animals. An agent that has high individual risk but low community risk would be in which Risk Group per the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules? B. C If an IACUC votes to suspend a protocol or animal activity, its decision cannot be overturned by any administrator at the organization (including the Institutional Official). B. Sponsors an accreditation program Members of the Council are chosen to serve based on their extensive experience in the fields of veterinary medicine, laboratory animal science or animal research, and their commitment to humane animal care and use. C If the IACUC decides that any animal activities must be stopped to protect either animals or humans, it is given clear regulatory authority to do so. It requires annual reports from its accredited facilities C. It conducts site visits every 3 years D. It is a government - sponsored agency 16. hose organizations that accept Public Health Service (PHS) or National Science Foundation (NSF) funding. Which of the following activities would EXCLUDE an animal from USDA category B? To protect individuals who have frequent contact with animals in a research facility. Which of the following best summarizes the information that must be provided when a database search is used to document a lack of alternatives? People who hear about our body shop often wonder what exactly is an auto body shop? Rodent fetuses along with other mammals are unconscious in utero, and hypoxia does not evoke a response. The IP injection site is on the animal's right side, close to the midline, in a caudal quadrant of the abdomen. If an organization accepts PHS funds or is registered with the USDA as a research organization, any protocol suspension must be reported by the Institutional Official to OLAW and USDA. Which statement about the Occupational Health and Safety Program is false? What is the easiest way to induce gas anesthesia for a mouse? Which of the following is true of AAALAC International? Which of the following sets of IACUC members are required by the AWA and/or PHS? A. Driving in the summer, winter, or rainy season may be to blame for the unpleasant odor inside the car. Which of the following activities would disqualify an animal from USDA category D? C The criteria used for intervention in research studies to prevent unnecessary pain and distress are called "humane endpoint criteria" because they describe when it is time to: euthanize an animal to prevent suffering; discontinue a painful procedure; and/or remove an animal from a study. B. x=3 t^2 The IACUC must be notified of the need for more animals to achieve statistical significance. D Written postoperative care records are kept for individual animals larger than rodents, but written records for groups of rodents are the norm. APPROXIMATELY 685 INSTITUTIONS ARE IN NORTH AMERICA, 111 INSTITUTIONS IN EUROPE, 13 INSTITUTIONS IN LATIN AMERICA AND THE CARIBBEAN, A In general, neonates are resistant to low oxygen levels (hypoxia), and accordingly carbon dioxide is not very effective as a euthanasia agent unless there is prolonged exposure. Today, more than 900 organizations worldwide are accredited. AAALAC International relies on three primary standards used by the Council to evaluate programs: UTSA & AAALAC Accreditation | Date of Inital Accrediation: October 26, 2010. Which of the following is an injectable anesthetic agent? Shock due to low blood volume and anemia. Unnecessary duplication of animal experiments is not allowed. Scientific reasons Which of the following would provide longer-acting pain relief in mice? A. Participating institutions receive an independent, unbiased expert assessment, and those that meet or exceed applicable standards are awarded accreditation. B. Compressed CO2 gas in cylinders is the only recommended source of carbon dioxide. Those organizations that conduct wildlife research. Institutions receiving PHS money must follow the "Guide" (OLAW oversight) and those accredited with AAALAC are subject to triannual program review and facility visits. B. If an animal undergoes non-survival surgery, no preparation of the surgical site is necessary because infections are not a concern. Antibiotics should be routinely administered to avoid wound infection. Which of the following statements concerning euthanasia of mice is true? ", Which of the following Guides is best used as a source of guidance for animals used in agricultural research and teaching? The IACUCs activities to ensure compliance benefit whom? B As the name implies, the Ag Guide is for agricultural animals used for agricultural (food and fiber) purposes. Evaluate the limit of $\Delta x / \Delta t$ as $\Delta t$ approaches zero to find the velocity at $t=3.00 \mathrm{~s}$. Which is a TRUE statement below regarding assessment of pain or distress in mice: A As a prey species, rodents are genetically programmed to mask signs of pain or distress. Which of the following statements about the postoperative period is FALSE? AAALAC Accreditation demonstrates to funding agencies and the general public that the animal care provided goes beyond minimum regulatory requirements. Which of the following Guides is best used as a source of guidance for animals used in agricultural research and teaching? Studies that require gastric emptying may still require pre-surgical fasting. Which of the following statements is TRUE? Dr. Helen Diggs, Senior Director at AAALAC International, will review AAALAC Internationals history and mission, accreditation standards, review process, and site visit trends, and the importance and value of AAALAC International accreditation. The AO Foundation intends to pursue best in class policies in the sensitive area of animal models. AAALAC International is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. C. The veterinarian cannot exempt an animal, even for medical reasons. Along with meeting all applicable local and national regulations, AAALAC accredited institutions must also demonstrate that they are achieving the standards outlined in the Guide for the Care and Use of Laboratory Animals (National Research Council, 1996). The floor space of the cage should be adequate to accommodate all mice on the cage floor, and respiration and heart beat cessation should be confirmed before disposal. A. Which of the following statements is correct about IP injections of mice? AAALAC accreditation also promotes scientific validitywhen research involves animals, reliable results depend on healthy animals and superior animal care. What diameter spherical balloon will just support the total weight? Which statement is true regarding anesthesia in mice? Which of the following statements is TRUE about injectable anesthetics compared with gaseous anesthetics used with mice? B. USDA (Animal Care Section) It is designed to provide general legal information and is not a substitute for legal advice provided by an attorney who is a member of One traditional framework that has been used to express the channel mechanism is the concept of flow. Which organization is responsible for monitoring Office of Laboratory Animal Welfare (OLAW). A properly performed search for alternatives will likely also confirm that the animal model is appropriate and that no alternative models exist. When the American Plains states were settled, no trees existed for the construction of housing. In the 1950s, the Professional Standards Committee of the Animal Care Panel (ACP), now the American Association for Laboratory Animal Science (AALAS), recognized a need for assuring the general public that laboratory animal research was conducted on a professional level, and that standard procedures were applied. D. Food should be withheld prior to surgery, but not water. Wire mesh floors Investigators should enroll in the local Occupational Health and Safety Program before beginning work with laboratory animals. C. Those organizations that accept U.S. Department of Agriculture (USDA) research funds. In this diverse landscape, AAALAC International uses performance standards to assure harmonization of accredited animal care and use programs globally. Mouse urine and pelt proteins are an allergic hazard to people. Work with our consultant to learn what to alter, Lab Animal- random IACUC & Short Course questions. B. C. Animals should be monitored during the postoperative period. To share information with other regulatory agencies Which task is NOT a function of the IACUC? This animal rights-related article is a stub. Which of the following best describes the purpose of the federally mandated "alternatives search" in an animal protocol? The use of a new anesthetic that provides better induction and a shorter recovery period. Which of the following organizations must comply with the PHS Policy when utilizing vertebrate animals for research, teaching, or testing? Lethal dose experiments in which animals are allowed to die without intervention. D. To search for procedures that may replace the use of animals, reduce the number of animals used, or refine the methodology to minimize animal pain or distress. ", A simple rule to prevent excess blood collection in an animal is to collect no more than what percentage of body weight as blood at one time? The IACUC can exempt an animal for scientific reasons. B. Retroorbital blood collection from a mouse performed under anesthesia. A. B. Regarding studies with infectious agents in animals, as the BSL and ABSL number increases from 1 to 4, what happens to the containment and safeguard practices? Which Public Health Service (PHS) organization is responsible for monitoring organizational compliance with PHS Policy? Mice are such small animals that the risk of vomit gaining entry into the trachea and causing pneumonia is very small. Non-vertebrates, laboratory mice, and laboratory rats. Which of the following is a mandated IACUC activity? After any preliminary work with the animals that is needed to finalize the design of the procedures, but before the formal study begins. B. Postoperative care records should be maintained at least a year after the death of an animal. Collecting tail snips from adult rodents for genotyping under local or general anesthesia. AAALAC Internationalis a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. AAALAC endorses the use of animals to advance medicine and science when there are no non-animal alternatives, and when it is done in an ethical and humane way. In this edition, we will bring you up to speed on AO VET activities over the past five months. C. Intervention must occur to remove an animal from a study, sometimes by euthanizing the animal. AAALAC International standards for accreditation are set forth by the Guide for the Care and Use of Laboratory Animals, established by the U.S. National Research Council in 2011. A. Using appropriate personal protective equipment can reduce the risk of allergies to mouse urine and pelt proteins. C. To provide a narrative justifying the use of the animal model based on experimental data. Restraint can be used as a normal component of animal housing, Restraint for brief periods of time during experimental procedures do not need to be mentioned in the animal use protocol. The Council on Accreditation is the group responsible for evaluating animal programs and determining their accreditation status. D. The use of computer modeling software to substitute for animal experiments. C. Nobody Work bare-handed to prevent loss of tactile sensation caused by disposable gloves. Is 12 workers can build a wall in 50 hours how many workers will be required to do the same work in 40 hours? Which of the following is a mandated IACUC activity? B The use of carbon dioxide in cylinders (not from dry ice) is the current recommended method of rodent euthanasia (AVMA recommendations on euthanasia) using a 20% replacement rate for the volume of carbon dioxide/cage or container. The standards in the Guide go above and beyond what is required by law. The fur should It provides a mechanism for peer evaluation of animal care and use programs B. A. A change from non-survival to survival surgery B. C Category D of the USDA report form applies to " animals upon which experiments, teaching, research, surgery, or tests were conducted involving accompanying pain or distress to the animals and for which appropriate anesthetic, analgesic, or tranquilizing drugs were used. In Section 3.4, new literature is explored and the assessment of impacts and projected risks is updated for a large number of natural and human systems. C The NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules deal only with recombinant infectious agents. D. Obtain an antimicrobial sensitivity panel or other therapeutic profile on the infectious agent. What best describes the oral gavage procedure? A. Which of statement is true about the euthanasia of neonatal mice? A. The organization and regulatory agencies only Along with meeting all applicable local and national regulations, AAALAC accredited institutions must also demonstrate that they are achieving the standards outlined in the Guide for the Care and Use of Laboratory Animals (Guide, NRC 2011); the Guide for the Care and Use of Agricultural Animals in Research and Teaching (Ag Guide, FASS 2010); and the European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes, Council of Europe (ETS 123). Experimental criteria are the only determinants of the euthanasia method that is acceptable for an animal. The Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching (the Ag Guide). B. A. Quickly and professionally. These "Member Organizations" include the American Heart Association, American Veterinary Medical Association, Asian Federation of Laboratory Animal Science Associations, European Society of Laboratory Animal Veterinarians, the National Association for Biomedical Research, and the Society of Toxicology. A. Non-survival surgery is surgery in which the animal is allowed to regain consciousness after the surgery. However, the latter should be performed under anesthesia and is not a preferred site because of the potential for damage to the eye when the technique is not done properly or when used repeatedly. B. In 1996, AAALAC changed its name to the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International). The exercise must take place outside the building. Institutional Animal Care and Use Committee. A Category E of the USDA report form applies to " animals upon which teaching, experiments, research, surgery or tests were conducted involving accompanying pain or distress to the animals and for which the use of appropriate anesthetic, analgesic, or tranquilizing drugs would have adversely affected the procedures, results, or interpretation of the teaching, research, experiments, surgery, or tests.". Contracting with a commercial enterprise to produce custom antibodies requires IACUC approval. A. Postoperative analgesia is generally unnecessary in rodents. A change in principal investigator. D. Dogs must be provided additional exercise regardless of the floor area of the cage. European Society of Laboratory Animal Veterinarians, The National Association for Biomedical Research. Changes in animal ownership and movement of animals between facilities during the postoperative period. B. IACUCs are not responsible for investigating allegations of mistreatment, misuse, or noncompliance, as it is the investigators role to do so. Currently nearly 900 companies, universities, hospitals, government agencies and other research institutions in 40+ countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. Which of the following is an example of refinement per the three Rs of Russell and Burch? Which of the following statements is/are TRUE regarding preparation of a mouse for surgery? Blood collections should be spaced far enough apart to prevent which of the following? Female mice have how many pairs of nipples? Animal density in the euthanasia chamber is not a concern. Which of the following organizations must comply with the PHS Policy when utilizing vertebrate animals for research, teaching, or testing? If an organization accepts PHS funds or is registered with the USDA as a research organization, any protocol suspension does not have to be reported by the Institutional Official to OLAW and USDA. D. Rodents and rabbits. Which of the following methods is considered acceptable for euthanizing mice? C. The animals and investigators only A protocol submitted to the IACUC should Some use accreditation as a symbol of qualityit shows that an institution is serious about setting, achieving and maintaining high standards for animal research programs. The Public Health Service (OLAW) Who is authorized to overturn a decision by an IACUC to suspend an activity involving animals? Over distension of the urinary and gall bladders. A microchip is injected subcutaneously with a hypodermic needle. Try BYJUS free classes today!No worries! A. Which of the following is the process of getting oxygen from the environment to the tissues of the body? Rodents are susceptible to subclinical infections after surgery. D The federally mandated search for alternatives helps to fulfill the requirement set forth in the AWA policies to consider alternatives to procedures that may cause more than momentary pain or distress. Describe the fluid-mosaic model of membrane structure. C. The list of citations and the date of the search. The program started in 1965, when leading veterinarians and researchers organized the American Association for Accreditation of Labo B Mice and rats have a tissue fold in their stomachs known as the limiting ridge that prevents them from vomiting. Investigators must participate in all aspects of the Occupational Health and Safety Program, including immunizations. Which of the following sets of IACUC members are required by the AWA and/or PHS? Assist with writing the basic science portions of a grant application. C. Typical services include rabies immunizations, tuberculosis testing, and tetanus immunizations. This concept represents the beginning of the effort to form an accreditation program for laboratory animal care and use. Which of the following statements is/are TRUE regarding preparation of a mouse for surgery? A. https://quizlet.com/393848410/animal-research-certification-test-flash-cards A. To provide an assurance by an information specialist that no alternative to the proposed animal model exists. AAALAC stands for the Association for Assessment and Accreditation of Laboratory Animal Care. More than 850 companies, universities, hospitals, government agencies and other research institutions in 36 countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. The Council conducts on-site visits and extensive evaluations, and provides ongoing advice to help organizations achieve and maintain accreditation. What is the goal of an occupational health and safety program? And perhaps most importantly, accreditation demonstrates a willingness to go above and beyond the minimums required by law, and assures the public that the institution is committed to the responsible use and treatment of animals in science. Having a selective small molecule tool to interrogate this kinase will help demonstrate that CAMKK2 inhibition can be Permission should be obtained from the IACUC and clinical administrators responsible for the area. In 1996, AAALAC changed its name to the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International). Accreditation standards further require A public relations specialist, veterinarian, person who is not a scientist, and person who is not affiliated with the organization. D Sterile technique is not required for non-survival surgery, but fur clipping and clean instruments are. AAALAC stipulates that accredited institutions observe any and all statutes and governmental regulations which bear upon animal care and use. A. (This is also called an exclusive or.). B. Anesthetize or sedate animals to reduce the chances of accidental human needle sticks. Which of the following sets of IACUC members are required by the AWA and/or PHS? B. What statement regarding adjunctive methods of euthanasia is TRUE? D. Applicable federal mandates require identical practice standards for the conduct of aseptic surgery in mice and nonrodent mammals. C. Mice will continue to groom themselves, even when in pain or distress. The hot air inside the balloon is at $70^{\circ} \mathrm{C}$ and $1 \mathrm{~atm}$. Humane endpoint criteria define the conditions under which: Which of the following statements is NOT true about AAALAC International? The organization, investigators, animals, and public health and welfare. Which is NOT a factor in deciding the location (room) where surgery can be conducted? Dogs, cats, and primates A straight needle is preferred for oral gavage in a 18 gram mouse because it prevents trauma to the esophagus. The Council is pleased to inform you that the program conforms with AAALAC International standards as set forth by the Guidefor the Care and Use of Laboratory Animals, NRC 2011. Therefore, FULL ACCREDITATION shall continue. In addition, more than 60 prestigious scientific, educational and other professional organizations are members of AAALAC International. Diffusion Let us complete them for you.

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